Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Francisco Bay Area

Best Southwest American Restaurants in SOMA

Price
Regions
Neighbourhoods
Top Rated
Dining Options
Seating Options
Award-winning
Accessibility

160 restaurants available nearby

A photo of Shelby's Rooftop restaurant
4.5
Awesome(311)
Price: Very Expensive
• Mexican • SOMA
Booked 54 times today
Shelby's Rooftop in the heart of SOMA, San Francisco, epitomizes the quintessential rooftop bar experience with its expertly-crafted cocktails and chic ambiance. Guests rave about the "spectacular views" and the vibrant, "mellow and classy" atmosphere, making it a standout for those seeking a premium bar, lounge, or bottle service venue. Patrons consistently highlight the "delicious" drinks and "great vibes," with special mentions of the mezcal cocktails being "absolutely super savory." The service at Shelby's is commended for being welcoming and attentive, ensuring a memorable visit. Whether you're celebrating a special occasion or just enjoying a casual night out, Shelby's Rooftop offers a breathtaking setting with "top-notch service" and an unmatched urban backdrop, making it a must-visit destination in San Francisco.
A photo of Buena Vida Cantina restaurant
4.4
Awesome(139)
Price: Moderate
• Mexican • SOMA
Booked 1 time today
Buena Vida Cantina in SOMA, San Francisco, is a haven for those craving Mexican comfort food with a twist. Chef Erik Hopfinger brings his culinary expertise to the table, offering dishes that are both traditional and innovative. Patrons rave about the authenticity and quality of the cuisine, with one diner exclaiming, "This place seriously holds up to some of the best food I’ve had in Mexico." The restaurant's commitment to fresh ingredients and balanced flavors shines through in their popular dishes like the carne asada and the uniquely delightful Mexican-style ramen. Buena Vida Cantina is not just about great food; it's about experiencing 'The Good Life' in a vibrant community setting, making every visit memorable with amazing food and exceptional service.
A photo of Marlowe restaurant
4.5
Awesome(2914)
Price: Moderate
• Mexican • SOMA
Booked 25 times today
Opened in 2010 and relocated to its current location in 2014, Marlowe is a New American bistro located in San Francisco’s Soma neighborhood in the former COCO500 space. Brought to you by Executive Chef Jennifer Puccio and award-winning San Francisco designer Ken Fulk, Marlowe focuses on classic comfort foods with flavorful twists, like Chef Puccio’s signature Marlowe Burger, seasonal poulet vert, brussels sprouts chips and quail egg topped steak tartare. Taking inspiration from the butcher shops of the past, Marlowe is designed with a sleek but comfortable feel, featuring white subway tiles, white marble, deep blue banquettes, wood block tables and specials listed on rolls of butcher paper.
A photo of BISTRO 888 restaurant
4.2
Awesome(1800)
Price: Expensive
• Mexican • SOMA
Booked 2 times today
Contemporary upscale Restaurant and Bar "BISTRO 888" in downtown San Francisco offers a modern Californian Cuisine designed by Executive Chef Norma Whitt. Along with serving delicious entrees using local ingredients, BISTRO 888 offer guests and extensive selection of wines, craft beer, and hand-crafted cocktails.
A photo of House of Prime Rib restaurant
4.8
Exceptional(15840)
Price: Very Expensive
• Mexican • Civic Center / Hayes Valley / Van Ness
Booked 274 times today
House of Prime Rib, nestled in the vibrant Civic Center / Hayes Valley / Van Ness neighborhood of San Francisco, is a bastion of exceptional American cuisine, specializing in an unparalleled prime rib experience. Celebrated for its 62-year legacy, this restaurant is a favorite for its "juicy and perfectly cooked" prime rib selections, from the English Cut to the King Henry Cut. Patrons rave about the "tender and flavorful" meat and the classic accompaniments like creamed spinach and Yorkshire pudding, emphasizing that it's not just a meal but an "unforgettable experience." The ambiance, described as energetic and celebratory, perfectly complements the top-notch service and old-school charm, making House of Prime Rib a must-visit for anyone seeking the quintessential American dining experience.
A photo of The Rotunda at Neiman Marcus - San Francisco restaurant
4.8
Exceptional(6103)
Price: Expensive
• Mexican • Downtown / Union Square
Booked 65 times today
The Rotunda at Neiman Marcus in San Francisco's Union Square is a quintessential destination for those seeking an exceptional American dining experience. Known for its elegant ambiance and meticulous service, The Rotunda offers a luxurious afternoon tea service that has won the hearts of locals and tourists alike. Patrons rave about the "delicious assortment of food" and "excellent ambience," highlighting the restaurant's ability to deliver a top-tier culinary experience. From the superb seafood selections like the praised shrimp and crab Louie salad to the classic American burger, every dish is crafted with excellence. Guests continually commend the Rotunda for its "outstanding service" and "beautiful setting," making it a must-visit for anyone looking to indulge in the finest American cuisine in a stunning, historic venue.
A photo of Wayfare Tavern restaurant
4.6
Exceptional(7830)
Price: Moderate
• Mexican • Financial District / Embarcadero
Booked 69 times today
At the heart of San Francisco's bustling Financial District, Wayfare Tavern stands as a beacon of American cuisine, offering a nostalgic yet refined dining experience. Chef Tyler Florence masterfully crafts a menu that captures the essence of early 20th century American fare, earning accolades from diners who rave about the "outstanding" food and service. Known for its moist and flavorful fried chicken and rustic yet elegant setting reminiscent of a Victorian parlor, Wayfare Tavern delivers a unique blend of tradition and innovation. Patrons consistently praise the "perfectly cooked" dishes and the tavern's ability to turn a meal into a cherished memory, making it a cornerstone of the San Francisco dining scene.
A photo of Historic John's Grill restaurant
4.7
Exceptional(7403)
Price: Expensive
• Mexican • Downtown / Union Square
Booked 95 times today
Nestled in the heart of Downtown San Francisco near Union Square, Historic John's Grill offers an exquisite seafood dining experience that has delighted guests since 1908. Known for its "expertly prepared fresh seafood," this landmark establishment is a favorite among celebrities and locals alike. Diners rave about the "amazing" lobster bisque and the "delicious" broiled halibut, highlighting the freshness and quality of the dishes. With its vibrant atmosphere and a nod to classic San Francisco charm, John's Grill continues to be a top choice for seafood lovers. As one patron put it, "Dinner was outstanding!! I had the broiled halibut which was so fresh and my husband had the Ribeye (also delicious). Our server Daniel was excellent! We will be back!!" Whether you're a local or just visiting, a meal at John's Grill is a must for anyone seeking the best seafood in the city.
A photo of Boulevard restaurant
4.7
Exceptional(9097)
Price: Very Expensive
• Mexican • Financial District / Embarcadero
Booked 34 times today
Boulevard, nestled in the vibrant Financial District/Embarcadero area of San Francisco, epitomizes the essence of Contemporary American cuisine with an innovative twist. The restaurant recently refreshed its approach, offering a multi-course prefix menu that dazzles diners. Reviewers rave about its culinary delights, describing dishes like the "out of this world" strawberry yuzu sundae and flavor-packed stuffed morels as highlights of their dining experience. Boulevard's commitment to quality is evident, with one patron noting, "Boulevard never disappoints! Excellent food. We have eaten there many times and it is always exceptional." This gem provides not just a meal but a memorable dining adventure, making it a must-visit for those seeking exceptional Contemporary American fare in a sophisticated setting.
A photo of Original Joe's - San Francisco restaurant
4.7
Exceptional(4209)
Price: Moderate
• Mexican • North Beach
Booked 62 times today
Original Joe's in San Francisco's vibrant North Beach is a true emblem of authentic Italian-American cuisine, offering a dining experience that's both classic and exceptional. Established over 80 years ago, it stands as the oldest of the Joe's restaurants nationwide, pioneering the renowned "Joe's Concept." With its iconic red leather booths and a menu celebrated for its Italian American flair, Original Joe's is a bastion of comfort food crafted with a Northern Californian twist. Glowing reviews often highlight dishes like the "best lasagna I have ever tasted" and praise its "incredible customer service." Whether it's the meatballs or the linguini and clams, each dish is a testament to the restaurant's commitment to quality and tradition, making it a must-visit for those seeking a genuine slice of San Francisco's culinary heritage.

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you

Discover best Mexican / Regional American (Southwestern) restaurants in SOMA

Discover a vibrant selection of Mexican restaurants in the SOMA district of San Francisco Bay Area, each offering a unique twist on traditional and contemporary Mexican cuisine. Nestled in this dynamic neighborhood, these eateries serve up an array of delicious dishes, from sizzling fajitas and hearty enchiladas to innovative tacos and fresh ceviches, catering to all palates and preferences. The dining scene in SOMA is renowned for its eclectic mix, with Mexican cuisine standing out for its authenticity and rich flavors, drawing both locals and tourists alike. Each restaurant emphasizes fresh, high-quality ingredients, often sourced locally, to create memorable dining experiences. The atmosphere across these venues ranges from casual and family-friendly to sophisticated and trendy, ensuring an appealing setting for any occasion. Whether you're in search of a quick bite or a leisurely meal, the Mexican restaurants in SOMA promise a delightful culinary journey. Enjoy expertly mixed margaritas and an extensive selection of tequilas that perfectly complement your meal, making your dining experience truly authentic.

  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo