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Best Southern American Restaurants in SOMA

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149 restaurants available nearby

A photo of Shelby's Rooftop restaurant
4.5
Awesome(341)
Price: Very Expensive
• Southern american • SOMA
Booked 32 times today
Shelby's Rooftop in San Francisco offers a top-notch Dining Bar experience that leaves diners raving about its exceptional ambiance and culinary delights. Perched high above the bustling 4th street, it provides breathtaking views that complement its contemporary-chic vibe. Guests adore the "amazing views of the city and bay," while indulging in expertly crafted cocktails and delectable shared plates like tuna tartare and lobster salad. The service is consistently praised, described as "fabulous" and "attentive," ensuring a memorable outing. Whether you're enjoying the lively indoor atmosphere or the cozy outdoor seating, Shelby's Rooftop promises a captivating and flavorful evening that truly stands out.
A photo of Marlowe restaurant
4.5
Awesome(2928)
Price: Moderate
• Southern american • SOMA
Booked 45 times today
Opened in 2010 and relocated to its current location in 2014, Marlowe is a New American bistro located in San Francisco’s Soma neighborhood in the former COCO500 space. Brought to you by Executive Chef Jennifer Puccio and award-winning San Francisco designer Ken Fulk, Marlowe focuses on classic comfort foods with flavorful twists, like Chef Puccio’s signature Marlowe Burger, seasonal poulet vert, brussels sprouts chips and quail egg topped steak tartare. Taking inspiration from the butcher shops of the past, Marlowe is designed with a sleek but comfortable feel, featuring white subway tiles, white marble, deep blue banquettes, wood block tables and specials listed on rolls of butcher paper.
A photo of BISTRO 888 restaurant
4.8
Exceptional(1795)
Price: Expensive
• Southern american • SOMA
Booked 15 times today
Contemporary upscale Restaurant and Bar "BISTRO 888" in downtown San Francisco offers a modern Californian Cuisine designed by Executive Chef Norma Whitt. Along with serving delicious entrees using local ingredients, BISTRO 888 offer guests and extensive selection of wines, craft beer, and hand-crafted cocktails.
A photo of House of Prime Rib restaurant
4.8
Exceptional(16007)
Price: Very Expensive
• Southern american • Civic Center / Hayes Valley / Van Ness
Booked 235 times today
House of Prime Rib in San Francisco is a beacon of authentic American cuisine, renowned for its "iconic" status and exceptional prime rib. With 62 years of unwavering dedication, it’s no surprise that this establishment garners glowing praise from loyal patrons who rave about its "festive" atmosphere and "superb" service. Guests continually highlight the "delicious" prime rib, which is described as "massive" and "perfectly cooked," making every visit a memorable experience. The lively ambiance and the meticulous attention from the staff ensure that every meal feels like a special occasion. Truly, House of Prime Rib offers a quintessential American dining experience.
A photo of The Rotunda at Neiman Marcus - San Francisco restaurant
4.7
Exceptional(6228)
Price: Expensive
• Southern american • Downtown / Union Square
Booked 81 times today
The Rotunda at Neiman Marcus in San Francisco is a shining example of exquisite American cuisine, offering a dining experience that combines tradition and elegance. Nestled in the heart of Union Square, this iconic venue is beloved for its "excellent service" and "delicious food," consistently leaving diners "extremely satisfied." The Rotunda's menu is celebrated for its innovative takes on American classics, like the "wonderful French 75 cocktail and lobster club sandwich." The chic setting, complete with beautiful views and festive decorations, enhances the atmosphere, making it a "must-visit" destination, especially during the holiday season. Experience the quintessential American dining delight at The Rotunda!
A photo of Wayfare Tavern restaurant
4.6
Exceptional(7874)
Price: Moderate
• Southern american • Financial District / Embarcadero
Booked 97 times today
Wayfare Tavern, nestled in San Francisco's bustling Financial District, stands as a beacon of exemplary Contemporary American cuisine. Chef Tyler Florence masterfully crafts dishes that transport diners to an era of authentic American flavors inspired by the early 20th century. The restaurant is celebrated for its "impeccably delicious" offerings, with standout dishes like the renowned "Mary’s Fried Chicken" and "deviled eggs" that leave patrons raving. The vibrant yet cozy Victorian ambiance complements the culinary delights, making it perfect for any occasion. With "phenomenal" service and a dedication to quality, Wayfare Tavern is a must-visit destination for food enthusiasts.
A photo of Boulevard restaurant
4.8
Exceptional(9151)
Price: Very Expensive
• Southern american • Financial District / Embarcadero
Booked 73 times today
Boulevard, located in San Francisco's vibrant Financial District, offers an exceptional dining experience that effortlessly blends Contemporary French and American cuisine. Guests rave about the "unbelievably delicious" dishes crafted with the "finest and freshest ingredients," beautifully presented and plated with elegance. The prix fixe menu offers a "multitude of choices," allowing diners to explore a variety of flavors. The restaurant's ambience is "stunningly beautiful," especially during the holiday season, making every meal memorable and festive. With top-notch service and a thoughtfully curated menu, Boulevard stands out as a must-visit destination for those seeking high-quality and authentic culinary delights.
A photo of Original Joe's - San Francisco restaurant
4.7
Exceptional(4299)
Price: Moderate
• Southern american • North Beach
Booked 120 times today
Original Joe's in North Beach, San Francisco, is a beacon of authentic American cuisine blended with rich Italian-American flavors. As a culinary institution for over 80 years, Original Joe’s offers a unique dining experience with its signature red leather booths and legendary smooth cocktails. Reviewers rave about its "fantastic drinks" and "great food," highlighting dishes like the Veal Marsala and house-made ravioli. The ambiance is described as "festive and friendly," making it perfect for any occasion. Whether you're a local or a tourist, Original Joe's promises a classic American experience that "never disappoints," truly making it a San Francisco landmark.
A photo of Historic John's Grill restaurant
4.7
Exceptional(7509)
Price: Expensive
• Southern american • Downtown / Union Square
Booked 59 times today
Historic John's Grill, nestled in the heart of San Francisco's Downtown/Union Square, is synonymous with exceptional seafood cuisine. Revered for its "remarkable Petrale Sole Almandine," this iconic eatery has captivated diners with its expertly prepared seafood dishes for over a century. Patrons frequently rave about the "best Fish and Chips ever" and the "fabulous clam chowder," showcasing the restaurant's commitment to authentic flavors and quality ingredients. The lively, historic ambiance, paired with attentive service and live jazz music, creates an unforgettable dining experience. John's Grill is unmistakably a San Francisco treasure, offering "great food at a great location in an historic setting."
A photo of Angler San Francisco restaurant
4.7
Exceptional(295)
Price: Very Expensive
• Southern american • Financial District / Embarcadero
Booked 53 times today
Angler San Francisco, a Michelin-starred gem nestled on the Embarcadero waterfront, offers a seafood experience that truly stands out. With a focus on fresh, seasonal ingredients, each dish is meticulously crafted by Chef de Cuisine Joe Hou, ensuring every bite is a "revelation." Diners rave about the "perfectly prepared" sea bream and "incredible" embered oysters, praising the restaurant's commitment to quality. The ambiance complements the exquisite flavors, with a warm décor and stunning views of the San Francisco Bay. Angler's seafood is not just a meal; it's an "absolutely stunning dining experience" that leaves patrons eager to return.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Melody
    San Francisco Bay Area •5 reviews
    5.0
    Dined 2 days ago
    It was the perfect date night spot. I came here solo and enjoyed a feast! The staffs are super attentive and service was beyond expectations. Food was very unique for a southern charm and taste great!
    More info
    PreludePrice: Expensive• Californian• Financial District / Embarcadero
    4.7
  • JeannieVIP
    San Francisco Bay Area •31 reviews
    5.0
    Dined 4 days ago
    This place is full of heartwarming flavors of Southern comfort food. Definitely a neighborhood gem. Every bite feels like a warm hug from home. The menu was full of classic favorites and the service team was friendly and attentive. They checked in with us often, perhaps a bit too often however, their dedication was not disappointing. The atmosphere strikes the perfect balance of kindness and wit, offering a welcoming space for laughter and great conversation. It’s the kind of place where delicious food meets delightful company, making our visit a memorable one. The corn muffins are out of this world, adding butter and honey. The fried chicken was crispy, moist and flavorful on the inside. BBQ pull pork sandwich was perfect, tender, tangy and sweet. Side dishes were macaroni & cheese and collard greens, prepared just right. Parking can be a challenge, street and meter parking. They accept reservations through OpenTable.
    More info
    Hard Knox Cafe on Clement StreetPrice: Moderate• Regional American (Southern)• Richmond District
    4.9
  • Angel
    San Francisco Bay Area •1 review
    5.0
    Dined on Mar 2, 2025
    It was my first time there. Great intimate setting. Everyone was super friendly. My only suggestion would be. Because of the name biscuits and blues… The biscuit other than the entertainment needs to be the star!
    More info
    Biscuits and BluesPrice: Expensive• Regional American (Southern)• Downtown / Union Square
    4.7
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